English
Hujayra madaniyatini hayot fanlari sohasida keng qo'llash bilan hujayra fabrikalari vaktsina ishlab chiqarish va tayyorlash, monoklonal antikorlar, ildiz hujayralari va somatik hujayra terapiyasi sohalarida iste'mol qilinadigan hujayra madaniyati sifatida keng qo'llaniladi. Hujayra o'sishi atrof-muhitga nisbatan qat'iy talablarga ega va mos osmotik bosim hujayralar yaxshi o'sish holatini saqlab turish uchun asosdir.
Gipertonik yoki gipotonik eritmalardagi hujayralar darhol qisqaradi, shishiradi va yorilib ketadi. Shuning uchun to'g'ri osmotik bosim hujayra fabrikalarida hujayralarni etishtirishning muhim shartlaridan biridir. Sutemizuvchilar va boshqa hayvon to'qimalarining hujayralarining osmotik bosimini in vitro sharoitida saqlab turish asosan natriy xlorid bilan bog'liq, ammo boshqa dielektriklarning osmotik bosimi munosabatlarini e'tiborsiz qoldirib bo'lmaydi. Osmotik bosim erituvchining birlik hajmidagi erigan moddaning molekulalari va ionlari soniga mutanosib bo'lib, madaniy muhitdagi ion balansi ma'lum bir nisbatga muvofiq boshqariladi. Oddiy osmotik bosimni saqlab turish nafaqat hujayra kuchlanishini saqlab turish, balki hujayra metabolizmini tartibga solishda ham muhim rol o'ynaydi. Hujayradan tashqari ionlarni tashish va ion konsentratsiyasi boshqa oziq moddalarni tashishni o'zgartirganligi sababli, u hujayralarning asosiy sintez tizimiga bevosita ta'sir qiladi.
Ideal osmotik bosim hujayralar turi va irqiga qarab o'zgaradi. Inson plazmasining osmotik bosimi 290 mmol / L ni tashkil qiladi, bu esa inson hujayralarini in vitroda etishtirish uchun ideal osmotik bosim hisoblanadi. Sutemizuvchilar hujayralarining osmotik bosimi odatda 290-300 mmol / L ni tashkil qiladi. Inson embrion o'pka fibroblastlari 250-325 mmol / L, sichqonlarda esa taxminan 310 mmol / L ni tashkil qiladi. Amaliy qo'llanmalarda 260-320 mmol / L osmotik bosim ko'pchilik hujayralar uchun mos keladi.
Hujayra fabrikalarida hujayralarni etishtirishda tegishli osmotik bosimning ahamiyati shubhasizdir. Bundan tashqari, tegishli harorat, gaz muhiti va pH qiymati, toksik bo'lmaganlik va sterillik hujayra madaniyati uchun asosiy shartlardir.
The FAI climbed 5.9 percent year-on-year in the first 11 months of 2018, quickening from the 5.7-percent growth in Jan-Oct, the National Bureau of Statistics (NBS) said Friday in an online statement.
The key indicator of investment, dubbed a major growth driver, hit the bottom in August and has since started to rebound steadily.
In the face of emerging economic challenges home and abroad, China has stepped up efforts to stabilize investment, in particular rolling out measures to motivate private investors and channel funds into infrastructure.
Friday's data showed private investment, accounting for more than 60 percent of the total FAI, expanded by a brisk 8.7 percent.
NBS spokesperson Mao Shengyong said funds into weak economic links registered rapid increases as investment in environmental protection and agriculture jumped 42 percent and 12.5 percent respectively, much faster than the average.
In breakdown, investment in high-tech and equipment manufacturing remained vigorous with 16.1-percent and 11.6-percent increases respectively in the first 11 months. Infrastructure investment gained 3.7 percent, staying flat. Investment in property development rose 9.7 percent, also unchanged.