English
Hujayra fabrikalarivaktsinani tayyorlash va lentiviral vektorlar kabi keng ko'lamli hujayra madaniyatida muhim rol o'ynaydi. Hujayralarni etishtirishda turli xil ifloslanishlar juda muammoli. Ifloslanish manbalari orasida mikroblar bilan ifloslanish nisbatan keng tarqalgan ifloslanish turi hisoblanadi.
Mikrob bilan ifloslanish hujayra fabrikalarida hujayralar oʻsishi natijasida oʻsadigan bakteriyalar, mogʻorlar, mikoplazmalar va qora qurtlar kabi turli ifloslanish manbalariga taalluqlidir. .
1. Bakteriyalar: Bakterial ifloslanish odatda ichak tayoqchalari, stafilokokklar va boshqalarni o'z ichiga oladi. Bunday ifloslanishni topish oson. Oddiy teskari mikroskop ostida qora va mayda qum. Madaniyat eritmasi odatda qisqa vaqt ichida sarg'ayadi. Suyuqlik aralashmaydi, ozgina chayqalish juda ko'p loyqalanishga olib keladi.
2. Mog'or: mog'or bilan ifloslanishning aksariyati Candida albicans, Aspergillus, xamirturush va boshqalar. Mog'or bilan ifloslanganidan so'ng, madaniy muhit qisqa vaqt ichida shaffof va loyqa bo'lib qoldi. Invert mikroskop ostida hujayralar orasidagi oʻzaro bogʻlangan filamentsimon va dendritik gifalar madaniyat muhitida suzayotganini koʻrish mumkin edi.
3. Mikoplazma: Mikoplazmaning kattaligi bakteriyalar va viruslar orasida bo'lib, u mustaqil tirik mikroorganizmdir. Umumiy antibiotiklarga emas, balki issiqlikka sezgir. Mikoplazmaning shakli o'zgaruvchan bo'lib, u asosan hujayra yuzasida va hujayralar orasida adsorbsiyalanadi. Elektron mikroskop ostida kuzatilganda markazda yuqori zichlikdagi zich granulalar mavjud bo'lib, ko'ndalang kesimi hujayra mikrovillisiga o'xshaydi.
4. Qora qurtlar: qora yelim qurtlari bilan ifloslanganidan keyin hujayralarda kichik qora dog'lar paydo bo'ladi va tartibsiz harakatlarni yuqori quvvatli mikroskop ostida ko'rish mumkin. Madaniyat muhitining loyqaligi aniq emas edi va u hujayralarning o'sish holatiga kam ta'sir ko'rsatdi.
Yuqoridagilar hujayra zavodlarida hujayralarni etishtirishda tez-tez uchraydigan mikrobial ifloslanishlardir. Ular hujayra o'sishiga turli xil ta'sir ko'rsatadi. Ushbu ifloslanishlarni nazorat qilish yaxshi hujayra o'sishini ta'minlashning asosiy chorasidir.
The FAI climbed 5.9 percent year-on-year in the first 11 months of 2018, quickening from the 5.7-percent growth in Jan-Oct, the National Bureau of Statistics (NBS) said Friday in an online statement.
The key indicator of investment, dubbed a major growth driver, hit the bottom in August and has since started to rebound steadily.
In the face of emerging economic challenges home and abroad, China has stepped up efforts to stabilize investment, in particular rolling out measures to motivate private investors and channel funds into infrastructure.
Friday's data showed private investment, accounting for more than 60 percent of the total FAI, expanded by a brisk 8.7 percent.
NBS spokesperson Mao Shengyong said funds into weak economic links registered rapid increases as investment in environmental protection and agriculture jumped 42 percent and 12.5 percent respectively, much faster than the average.
In breakdown, investment in high-tech and equipment manufacturing remained vigorous with 16.1-percent and 11.6-percent increases respectively in the first 11 months. Infrastructure investment gained 3.7 percent, staying flat. Investment in property development rose 9.7 percent, also unchanged.