Applikazzjoni tal-Fabbrika taċ-Ċelloli fil-Kultura ta' Rotavirus

Wed May 18 12:09:03 CST 2022

Cell factoryIt-teknoloġija tal-kultura hija waħda mill-metodi effettivi għall-kultura taċ-ċelluli fuq skala kbira u l-amplifikazzjoni tal-virus. Għandu l-vantaġġi ta 'riskju baxx ta' kontaminazzjoni, amplifikazzjoni konvenjenti, u iffrankar ta 'spazju. Il-kultura ta 'rotavirus orali hija aspett wieħed ta' l-applikazzjoni tagħha.

Rotavirus huwa wieħed mill-patoġeni ewlenin li jikkawżaw dijarea fit-trabi u tfal żgħar. Prinċipalment jinfetta ċelluli epiteljali intestinali żgħar, u jikkawża ħsara fiċ-ċelluli u dijarea. Ir-rotta tal-infezzjoni hija r-rotta ippurgar-orali, u l-manifestazzjonijiet kliniċi huma gastroenterite akuta, dijarea osmotika, u sintomi ta 'deidrazzjoni f'każijiet severi. It-tilqim kontra r-rotavirus fi trabi u tfal żgħar huwa l-miżura ewlenija biex tipprevjeni l-marda.

Imqabbla mal-kultura tradizzjonali tal-flixkun tar-rombli, it-teknoloġija tal-kultura tal-fabbrika taċ-ċelluli hija kontenitur effiċjenti tal-kultura taċ-ċelluli. Il-wiċċ tiegħu huwa ttrattat b'mod speċjali biex ikollu assorbiment uniformi u kontinwu taċ-ċelluli, li jista 'jippromwovi b'mod effettiv it-tkabbir aderenti taċ-ċelloli u jqassar il-perjodu tal-kultura. Ittejjeb il-prodott. Wara t-tilqim bir-rotavirus, iċ-ċelloli mhumiex affettwati minn forzi ta 'shear likwidi, li jiffaċilita r-replikazzjoni virali kontinwa għal ħsad multipli. L-esperimenti wrew li wara t-tilqim bil-virus tar-razza La, ir-rata tal-waqgħa tal-virus fil-fabbrika taċ-ċelluli tikber aktar malajr, u t-titer tal-virus jilħaq 6.0-6.5lgCCID/ml fi 3 ijiem. Iċ-ċelloli maħsuda ma jaqgħux, iżda xorta huma rranġati indaqs. Il-mezz ta 'manutenzjoni kompla jiġi kkultivat, u ċ-ċelloli ma waqgħux sat-tielet ħsad tal-mezz tal-virus.

B'mod ġenerali, wara li t-teknoloġija tal-kultura tal-fabbrika taċ-ċelluli tiġi applikata għall-kultura ta' rotavirus, taħdem tajjeb f'termini ta 'tkabbir taċ-ċelluli ir-rata u l-ħinijiet tal-ħsad, u huwa kontenitur tal-kultura taċ-ċelluli effiċjenti.

The FAI climbed 5.9 percent year-on-year in the first 11 months of 2018, quickening from the 5.7-percent growth in Jan-Oct, the National Bureau of Statistics (NBS) said Friday in an online statement.

The key indicator of investment, dubbed a major growth driver, hit the bottom in August and has since started to rebound steadily.

In the face of emerging economic challenges home and abroad, China has stepped up efforts to stabilize investment, in particular rolling out measures to motivate private investors and channel funds into infrastructure.

Friday's data showed private investment, accounting for more than 60 percent of the total FAI, expanded by a brisk 8.7 percent.

NBS spokesperson Mao Shengyong said funds into weak economic links registered rapid increases as investment in environmental protection and agriculture jumped 42 percent and 12.5 percent respectively, much faster than the average.

In breakdown, investment in high-tech and equipment manufacturing remained vigorous with 16.1-percent and 11.6-percent increases respectively in the first 11 months. Infrastructure investment gained 3.7 percent, staying flat. Investment in property development rose 9.7 percent, also unchanged.